I bought Goolgle Chromecast with Goolgle TV just this mid June 2022, I started facing issues in remote, the buttons "Home" "Back" "Netflix" "Youtube" no longer working. Not sure what is the fix? Should i replace it? very weird and at least the Power Mute Volume buttons working.
Assuming the batteries are good (maybe check them in another device), try these steps:
In most cases, your remote will pair automatically after you insert the batteries. If it doesn’t, follow the steps on the TV screen, or press and hold the Back and Home buttons on the remote for 3 seconds.