Hello @Dave31
Thank you for reaching out to the Nest community to resolve your compatibility questions. Don't worry; I'm here to help you with that.
Could you please share with me a picture of your Trane thermostat wiring? This is to make sure of your system's functions; it will be helpful.
Also, Let me provide some information about the wires compatible to our devices in this article: Identify a Thermostat Wire
Please feel free to keep posting your questions; I'll do my best to find a solution for you.
Best regards,
Douglas.
